Gene information
Official symbol CD14
Official full name CD14 molecule
Gene type protein-coding gene
Chromosome5q31.3
Gene familyCD molecules; Scavenger receptors
Resources
Entrez Gene 929
HGNC HGNC:1628
Ensembl ENSG00000170458
Vega OTTHUMG00000129507
UCSC uc021yej.1
GO terms: 33 records
GO Description Category LogP Number of genes Detail
GO:0001530 lipopolysaccharide binding GO Molecular Functions -6.94413823 11 More
GO:0002221 pattern recognition receptor signaling pathway GO Biological Processes -6.97185167 18 More
GO:0002237 response to molecule of bacterial origin GO Biological Processes -48.4964960 93 More
GO:0002764 immune response-regulating signaling pathway GO Biological Processes -3.80325753 14 More
GO:0006897 endocytosis GO Biological Processes -8.07395492 24 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0009266 response to temperature stimulus GO Biological Processes -12.1149168 32 More
GO:0009897 external side of plasma membrane GO Cellular Components -28.0033937 46 More
GO:0010008 endosome membrane GO Cellular Components -3.11007663 16 More
GO:0010035 response to inorganic substance GO Biological Processes -29.1720710 89 More
GO:0010038 response to metal ion GO Biological Processes -20.5090881 61 More
GO:0030100 regulation of endocytosis GO Biological Processes -14.0757782 22 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031225 anchored component of membrane GO Cellular Components -4.51589396 20 More
GO:0031663 lipopolysaccharide-mediated signaling pathway GO Biological Processes -14.0408172 12 More
GO:0032496 response to lipopolysaccharide GO Biological Processes -45.257773 87 More
GO:0032649 regulation of interferon-gamma production GO Biological Processes -12.4733429 27 More
GO:0032677 regulation of interleukin-8 production GO Biological Processes -20.0046302 33 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0033218 amide binding GO Molecular Functions -9.50305686 47 More
GO:0042277 peptide binding GO Molecular Functions -10.2245210 22 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0045807 positive regulation of endocytosis GO Biological Processes -11.0143833 14 More
GO:0060627 regulation of vesicle-mediated transport GO Biological Processes -25.1756709 46 More
GO:0071216 cellular response to biotic stimulus GO Biological Processes -28.1549742 59 More
GO:0071219 cellular response to molecule of bacterial origin GO Biological Processes -28.3848077 56 More
GO:0071222 cellular response to lipopolysaccharide GO Biological Processes -26.0381191 52 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:0097305 response to alcohol GO Biological Processes -17.4096682 46 More
GO:0098552 side of membrane GO Cellular Components -22.4625650 48 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04145 Phagosome KEGG Pathway -11.4012504 17 More
hsa05221 Acute myeloid leukemia KEGG Pathway -2.91912787 5 More
Drug-Gene interaction
view
Related drugs: 2 records
Drug name Interaction type Source PMID View
ic14 inhibitor TdgClinicalTrialChemblInteractionsTTD view
lovastatin NCI 7506029 view
Related studies: 8 records
Molecular factor Omics type Application Objective MI type Reference
NM_000591.4:c.-260C>T genomics myocardial infarction[diagnosis] myocardial infarction Unkelbach K et al. Arterioscler Thromb Vasc Biol. 1999
NM_000591.4:c.-260C>T genomics myocardial infarction[diagnosis] myocardial infarction Hubacek JA et al. Circulation. 1999
NM_000591.4:c.-260C>T genomics acute myocardial infarction[diagnosis] acute myocardial infarction Shimada K et al. Am J Cardiol. 2000
NM_000591.4:c.-260C>T genomics myocardial infarction[diagnosis] myocardial infarction Hohda S et al. Jpn Heart J. 2003
NM_000591.4:c.-260C>T genomics myocardial infarction[diagnosis] myocardial infarction Morange PE et al. Atherosclerosis. 2005
NM_000591.4:c.-260C>T genomics myocardial infarction[diagnosis] myocardial infarction Li Y et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2005
NM_000591.4:c.-260C>T genomics apolipoprotein A-I[other] acute myocardial infarction Lima-Neto LG et al. J Thromb Thrombolysis. 2013
NM_000591.4:c.-260C>T genomics high-density lipoprotein cholesterol[other] acute myocardial infarction Lima-Neto LG et al. J Thromb Thrombolysis. 2013
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